BUY MESTEROLONE (PROVIRON) (25 MG/TAB. – 50 TABS)

Main Description

Mesterolone 25 is an oral tablet containing 25 mg of mesterolone, an androgen used according to the supplied product information for conditions associated with deficient endogenous androgen formation in adult males. Mesterolone is described as an orally active androgen that does not aromatise to oestrogen. The supplied information states that it can act as an androgen substitute where natural androgen production is insufficient.

The product information describes mesterolone as being used in several male health settings, including potency disturbances, hypogonadism, declining physical and mental alertness associated with reduced androgen formation, and certain cases of infertility. Its pharmacological activity is associated with androgen-dependent tissues and may contribute to the management of symptoms associated with androgen deficiency.

Each tablet contains 25 mg of mesterolone. The product is supplied as 50 uncoated tablets in one bottle and is intended for oral administration.

Key Product Information

• Product: Mesterolone (Proviron)
• Strength: 25 mg per tablet
• Active ingredient: Mesterolone
• Dosage form: Uncoated tablet
• Route: Oral
• Pack size: 50 tablets
• Molecular formula: C20H32O2
• Molecular weight: 304.46688 g/mol
• CAS number: 1424-00-6
• Market status: Prescription
• Company: Hilma Biocare

Clinical Pharmacology

According to the supplied information, mesterolone helps compensate for reduced androgen formation and is intended to provide androgenic activity without conversion to oestrogen through aromatisation. It is described as having an effect on androgen-dependent tissues and may influence symptoms associated with reduced endogenous androgen production.

The supplied information also states that mesterolone may reduce sex hormone-binding globulin (SHBG), potentially increasing the proportion of free testosterone. At the recommended therapeutic dosage described in the source material, mesterolone is stated not to impair spermatogenesis.

Indications

The supplied product information lists mesterolone for several male conditions associated with androgen deficiency, including:

• Potency disturbances associated with androgen deficiency.
• Hypogonadism and androgen-deficiency-related symptoms.
• Declining physical activity and mental alertness associated with reduced androgen formation.
• Certain infertility conditions, including oligozoospermia and insufficient Leydig-cell secretion.
• Androgen replacement after puberty, where clinically appropriate.

The source material states that treatment of some infertility conditions may improve sperm count, sperm quality and fructose concentration. Individual suitability and treatment decisions should be determined by a qualified healthcare professional.

Contraindications and Precautions

Mesterolone is contraindicated in patients with known or suspected carcinoma of the prostate or testis. The supplied information recommends that the product be used only in male patients.

Regular prostate examinations are recommended as a precaution during androgen therapy. Patients should discuss their medical history and any existing prostate-related symptoms with their doctor before treatment.

Adverse Reactions

The supplied product information reports oily skin, increased body-hair growth and possible hair loss at higher doses in genetically predisposed individuals.

As with other androgenic medicines, patients should report unexpected or persistent adverse effects to their healthcare professional.

Dosage and Administration

The supplied information provides different dosing schedules depending on the clinical indication. For declining physical activity and potency-related problems, it describes 25 mg three times daily during the first week, followed by 25 mg once or twice daily for the specified treatment period.

For hypogonadism, the supplied information gives 25 mg two to three times daily.

For oligozoospermia, it gives 25 mg two to three times daily for a full spermatogenic cycle of approximately three months.

These dosing schedules are reproduced from the supplied product information and should not be interpreted as individual medical advice. Mesterolone is a prescription medicine and should be used only according to the prescribing clinician’s instructions.

Presentation

Mesterolone 25 mg uncoated tablets are supplied as 50 tablets in one bottle.

Storage

Store in a cool, dry place between 15–25°C and protect from light.