BUY LEVOTHYROXINE SODIUM T4 (100 MCG/TAB. – 50 TABS)
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Product Specifications
- Product: T4, Levothyroxine Sodium
- Strength: 100 mcg
- Active Ingredient: Levothyroxine Sodium
- Molecular Formula: C₁₅H₁₁I₄NO₄
- Molecular Weight: 776.87 g/mol
- CAS Number: 51-48-9
- Dosage Form: Tablet
- Route: Oral
- Market Status: Prescription
- Company: Hilma Biocare
- Pack Size: 50 uncoated tablets
- Storage: 15–25°C, protected from light
LEVOTHYROXINE SODIUM T4 Main Product Description
Levothyroxine Sodium T4 100 mcg is an oral tablet containing levothyroxine sodium, the synthetic L-form of thyroxine (T4), one of the principal hormones naturally produced by the thyroid gland. Levothyroxine is designed to provide thyroid hormone replacement when the body does not produce sufficient thyroid hormone naturally.
Thyroid hormones have an important role in regulating metabolic activity throughout the body. After administration, levothyroxine (T4) can be converted into its biologically active metabolite, L-triiodothyronine (T3). Both T4 and T3 interact with thyroid hormone receptors within cells and influence gene transcription and protein synthesis. Through these mechanisms, thyroid hormones contribute to the regulation of energy metabolism, growth and development and numerous other physiological processes.
The supplied product information identifies Levothyroxine Sodium T4 100 mcg as a prescription medicine intended for oral administration. Each tablet contains 100 micrograms of levothyroxine sodium, and the product is supplied as 50 uncoated tablets in one bottle.
Levothyroxine is primarily used medically for the treatment of hypothyroidism and other conditions in which thyroid hormone production is below the required level. Reduced thyroid hormone production may occur because of naturally occurring thyroid disease, damage caused by certain treatments or medicines, radiation exposure, or surgical removal of thyroid tissue. In these circumstances, levothyroxine provides thyroid hormone replacement.
The absorption of orally administered levothyroxine occurs mainly in the small intestine. The supplied information reports gastrointestinal absorption of approximately 40–80%, with most absorption taking place in the jejunum and upper ileum. Food and certain substances can reduce absorption, which is why consistent administration in relation to meals is important when using prescribed levothyroxine.
The supplied pharmacokinetic information reports that levothyroxine has a relatively long elimination half-life. In people with normal laboratory results, the reported half-life is approximately 6–7 days. It may be approximately 9–10 days in people with hypothyroidism and approximately 3–4 days in people with hyperthyroidism. Thyroid hormones are primarily eliminated through the kidneys, with the remaining portion eliminated through the gastrointestinal tract.
Levothyroxine requires careful dose selection because excessive thyroid hormone exposure can produce symptoms associated with an overactive thyroid state. The supplied adverse-effect information includes weight loss, heat intolerance, sweating, anxiety, difficulty sleeping, tremor and increased heart rate. Cardiovascular effects are particularly important in susceptible patients.
Levothyroxine is contraindicated in certain circumstances, including hypersensitivity to levothyroxine sodium or formulation components, thyrotoxicosis and uncorrected adrenal insufficiency. The supplied information also identifies acute myocardial infarction as a contraindication. Patients with cardiovascular disease, angina, coronary artery disease or hypertension require particular caution and appropriate medical supervision.
The timing of administration can affect levothyroxine absorption. The supplied information recommends taking the medicine on an empty stomach approximately 30–60 minutes before food, with water. Calcium and iron supplements can interfere with absorption and should be separated from levothyroxine according to professional medical advice. Other medicines and substances, including certain antacids, bile-acid sequestrants and other gastrointestinal products, may also affect absorption.
Levothyroxine treatment can interact with diabetes management. Thyroid hormone replacement may alter requirements for insulin or other antidiabetic medicines. Patients with diabetes should therefore have their treatment monitored by their healthcare professional. LEVOTHYROXINE SODIUM T4 LEVOTHYROXINE SODIUM T4 LEVOTHYROXINE SODIUM T4 LEVOTHYROXINE SODIUM T4 LEVOTHYROXINE SODIUM T4
Special care is also required in older adults and people with long-standing hypothyroidism. The supplied information recommends gradual introduction in patients over 50 years of age and those with prolonged hypothyroidism, particularly because increasing metabolic demand may place additional stress on the cardiovascular system.
Long-term thyroid hormone treatment should be monitored through appropriate clinical assessment and laboratory testing. The objective of treatment is generally to maintain thyroid hormone levels within the appropriate therapeutic range rather than to produce excessive metabolic stimulation.
The product information supplied also discusses the use of T4 in bodybuilding and weight-management contexts. These uses should be clearly distinguished from established medical treatment. Levothyroxine should not be promoted as a general weight-loss product or used to accelerate metabolism without a medically established indication. Excess thyroid hormone can cause significant cardiovascular and metabolic complications.
The 100 mcg tablet strength provides a defined dose for prescribed thyroid hormone replacement. However, the appropriate dose varies between individuals according to factors such as age, body weight, thyroid function, underlying medical condition, other medicines and laboratory results. Treatment therefore requires individual assessment and monitoring rather than a universal dosing schedule.
Levothyroxine Sodium T4 100 mcg should be stored in a cool, dry environment between 15 and 25°C and protected from light. The tablets should remain in their original packaging where possible and be kept away from children.
Overall, Levothyroxine Sodium T4 100 mcg is a prescription oral thyroid hormone replacement product containing levothyroxine sodium. Its established medical role is the replacement of thyroid hormone in appropriate patients, particularly those with hypothyroidism. Because both insufficient and excessive thyroid hormone levels can have significant health consequences, treatment should be undertaken under appropriate medical supervision with dose adjustment based on clinical response and laboratory monitoring.
Pharmacokinetics
Absorption
Oral absorption is reported at approximately 40–80%, occurring predominantly in the jejunum and upper ileum. Fasting can increase absorption, while certain foods, medicines and malabsorption conditions may reduce it.
Half-Life
The supplied information reports:
- Normal thyroid function: approximately 6–7 days
- Hypothyroidism: approximately 9–10 days
- Hyperthyroidism: approximately 3–4 days
Elimination
Approximately 80% of thyroid hormone elimination is reported to occur through the kidneys, with the remainder eliminated through the stool.
Medical Use
Levothyroxine is used primarily as thyroid hormone replacement for hypothyroidism and other conditions associated with inadequate endogenous thyroid hormone production.
It may be required following thyroid surgery or damage to the thyroid gland caused by certain treatments or medicines.
The bodybuilding and weight-loss applications mentioned in the supplied source should not be treated as established medical indications.
Contraindications
According to the supplied information, levothyroxine is contraindicated in patients with:
- Hypersensitivity to levothyroxine sodium or formulation components
- Thyrotoxicosis of any cause
- Uncorrected adrenal insufficiency
- Acute myocardial infarction
Medical assessment is particularly important in patients with cardiovascular disease.
Side Effects
Adverse effects are generally associated with excessive thyroid hormone exposure or inappropriate dosing.
Possible symptoms include:
- Weight loss
- Heat intolerance
- Excessive sweating
- Anxiety
- Insomnia
- Tremor
- Nervousness
- Increased heart rate
Severe allergic reactions are uncommon but may include difficulty breathing or swelling of the face or tongue and require urgent medical attention.
Precautions & Warnings
Particular caution is required in:
- Older adults
- Patients with cardiovascular disease
- Patients with angina
- Patients with coronary artery disease
- Patients with hypertension
- Patients with long-standing hypothyroidism
- Patients with adrenal insufficiency
- Patients with diabetes
Thyroid hormone replacement should be carefully titrated and monitored. Excessive thyroid hormone exposure can increase cardiovascular strain and may contribute to bone loss over time. LEVOTHYROXINE SODIUM T4 LEVOTHYROXINE SODIUM T4 LEVOTHYROXINE SODIUM T4
Drug & Food Interactions
Several substances may reduce levothyroxine absorption, including:
- Calcium supplements
- Iron supplements
- Aluminium-containing antacids
- Magnesium-containing antacids
- Sucralfate
- Cholestyramine
- Colestipol
- Kayexalate
- Certain soy-containing products
The supplied information recommends separating calcium and iron supplementation from levothyroxine administration.
Levothyroxine can also affect the requirements for insulin and other diabetes medicines. Patients should inform their healthcare professional about all prescription medicines, supplements and other products they use.
Dosage & Administration
The appropriate levothyroxine dose is individualised according to thyroid function, age, body weight, underlying condition, cardiovascular status and laboratory results.
The supplied information recommends taking levothyroxine on an empty stomach approximately 30–60 minutes before food, with a glass of water.
Patients should follow the dose prescribed by their doctor and should not increase, decrease or discontinue treatment without medical advice.
The bodybuilding-oriented dosing and cycling information contained in the source material should not be presented as a recommended use of prescription thyroid hormone.
Presentation
Levothyroxine Sodium 100 mcg uncoated tablets:
50 tablets in 1 bottle.
Storage
Store in a cool, dry place between 15–25°C.
Protect from light.
Keep out of reach of children.
